VALIDATION DATA

MEASUREMENT PROPERTIES
Limitations >=5 European languages (English)
Observations
1. RELIABILITY
A. Internal Consistency Tested
Cronbach's (Describe)

The Crohnbach α values showed a  good level  of  internal consistency  (i.e.,   approximating  0.8): pain (0.82), physical function (0.92),social function (0.8), general health perception  (0.72) and mental function (0.77)

B. Reliability intraobserver or test-retest Tested
Continuous scores: intraclass
correlation coefficient (ICC)
Dichotomus: Cohen kappa (Describe)

All questions gave high degrees of  reproducibility (test–retest  repeatability)  and 26 of  41 questions gave a kappa score ≥70 indicating substantial  agreement between the first and second administration: pain (0.68 (0.64-0.7)), physical function (0.74 (0.69-0.8)), social function (0.79 (0.65-0.9)), general health perception  (0.66 (0.64-0.74)) and mental function (0.65 (0.54-0.72)).

C. Reliability interobserver or Measurement error Not Tested
Standard error of measurement (SEM),
smallest detectable change (SDC) or
Limits of agreement (LoA) (Describe)
2. VALIDITY
A. Content validity: face validity Not Tested
Expert opinion (relevance and
comprehensiveness) (Describe)
B. Construct Validity:
Structural validity
Tested
Hypotheses-testing Tested
Cross-cultural validity Tested
Brief Description

Convergent validity (percentage of question scores correlating with the domain score better than 0.40) was good: pain (100%), physical function (94%), social function (100%), general health perception (100%) and mental function (98%)

C. Criterion validity Tested
Comparison with a 'gold standard' Continuous scores:
correlations, ROC curves Dichotomus:
Sensitivity & Specificity (Describe)

Significant correlations existed between scores of similar domains of QUALEFFO and   SF-36 for  pain (0.74),   physical   function (0.81) and mental  function (0.80).  

The ROC curve analysis of QUALEFFO indicated that all five domains were significantly predictive of vertebral fractures than controls: pain (0.77 (0.03)), physical function (0.78 (0.03)), social function (0.67 (0.03)), general health perception (0.71 (0.03)) and mental function (0.64 (0.03)).