| Name of the Instrument/Tool | Disease Extent Index (DEI) |
| First Description |
de Groot K, Gross WL, Herlyn K, Reinhold-Keller E. Development and validation of a disease extent index for Wegener's granulomatosis. Clin Nephrol. 2001 Jan;55(1):31-8. PMID: 11200865. |
| Year | 2001 |
| Domains | |
| Concept of constructs | Disease activity |
| Population/Disease | Disease specific |
| Originally developed for | ANCA-associated vasculitis (AAV) |
| Other rheumatic diseases where can be applied (only if validated) |
--- |
| Additional population with no rheumatic diseases |
No |
| Language: Originally published in | English |
| Available in Language | German |
| REFERENCE IDENTIFICATION | |
| Author/s | de Groot, K. and Gross, W. L. and Herlyn, K. and Reinhold-Keller, E. |
| Title | Intra- and inter-rater reliability of endonasal activity estimation in granulomatosis with polyangiitis (Wegener's) |
| Journal | Clin Exp Rheumatol |
| Year | 2001 |
| Vol | 30 |
| Num | 70 |
| Pages | 22-8 |
| Country | Germany |
| Language | English |
| Other references of interest | |
| Link | https://pubmed.ncbi.nlm.nih.gov/17519271/ |
| Brief Description |
Elevated relapse rate under oral methotrexate versus leflunomide for maintenance of remission in Wegener's granulomatosis. |
| Instrument/Tool Translations References | |
| No other References. | |
| DEVELOPER CONTACT INFORMATION | |
| Correspondence to | K. de Groot |
| kirsten@de-groot.de | |
| Address | Department of Otorhinolaryngology, Head and Neck Surgery, University of Kiel, Kiel, Germany. |
| Website | --- |
| Available | --- |
| Links | --- |
| DESCRIPTION OF THE INSTRUMENT | |
| Type Of Measure | Score |
| Brief Description |
The DEI is valid, reliable, easy, quick to perform and highly reproducible to assess disease extent (staging) and activity (grading) in patients with ANCA-associated vasculitides. |
| Number of Items | 11 |
| Range | 0-21 |
| Responses options/scale |
Yes Scale |
| Developed for | Clinical practice |
| PRACTICAL APPLICATION | |
| Method of administration | Physician |
| Recommendations to score |
Some items are scored higher (weighted score) |
| Score Interpretation | Higher scores indicate higher disease extent. |
| Cut-off points | --- |
| Cut-off points applied to | --- |
| Smallest detectable change if described | - |
| Smallest detectable change applied to | --- |
| Completion time by the patient | - minutes |
| Scoring time by the assessor | 1 minutes |
| Training to score | Not necessary |
| Strengths | Useful in clinical practice & research, Easy to use |
| Limitations | --- |
| OTHER COMMENTS | |
| Other Comments | --- |