VALIDATION DATA

MEASUREMENT PROPERTIES
Limitations >=5 European languages (English)
Observations
1. RELIABILITY
A. Internal Consistency Tested
Cronbach's (Describe)

Cronbach's α = 0.87

B. Reliability intraobserver or test-retest Tested
Continuous scores: intraclass
correlation coefficient (ICC)
Dichotomus: Cohen kappa (Describe)

Test–retest reliability was good when scores were repeated after a 24-hour interval (r = 0.96, p<0.001) in inpatients with AS.

ICC = 0.86

C. Reliability interobserver or Measurement error Tested
Standard error of measurement (SEM),
smallest detectable change (SDC) or
Limits of agreement (LoA) (Describe)

ICC = 0.99 (2 independent observers - rheumatologists, not patient-scored)

2. VALIDITY
A. Content validity: face validity Tested
Expert opinion (relevance and
comprehensiveness) (Describe)

Items were generated in an expert group of 3 rheumatologists experienced in the management of patients with AS. Patients were not involved in the development process.

B. Construct Validity:
Structural validity
Tested
Hypotheses-testing Tested
Cross-cultural validity Not Tested
Brief Description

Principal component analysis was used to refine items.

DFI discriminates between AS inpatients and outpatients, AS patients with high and low disease activity, and AS smokers and non-smokers.

C. Criterion validity Tested
Comparison with a 'gold standard' Continuous scores:
correlations, ROC curves Dichotomus:
Sensitivity & Specificity (Describe)

Criterion validity was assessed using a multiple regression model, including the DFI score, and clinically measured morning stiffness, number of nocturnal awakenings, chest expansion, Schober’s test, hand-ground distance, self-physiotherapy, and pain. The correlation coefficient between the independent variables and the functional index (dependent variable) was R2 = 0.41.