VALIDATION DATA

MEASUREMENT PROPERTIES
Limitations
Observations
1. RELIABILITY
A. Internal Consistency Not Tested
Cronbach's (Describe)
B. Reliability intraobserver or test-retest Not Tested
Continuous scores: intraclass
correlation coefficient (ICC)
Dichotomus: Cohen kappa (Describe)
C. Reliability interobserver or Measurement error Not Tested
Standard error of measurement (SEM),
smallest detectable change (SDC) or
Limits of agreement (LoA) (Describe)
2. VALIDITY
A. Content validity: face validity Not Tested
Expert opinion (relevance and
comprehensiveness) (Describe)
B. Construct Validity:
Structural validity
Tested
Hypotheses-testing Tested
Cross-cultural validity Not Tested
Brief Description

Construct validity was tested by computing the standardized mean difference (SMD) against the decision to change treatment (defined as new prescription or increasing dose/switching urate-lowering treatment not related to adverse reactions, and/or prescription of symptomatic drugs such as colchicine/nonsteroidal anti-inflammatory drugs/intra-articular or systemic glucocorticoids, or the occurrence of a gout flare within the following 6 months), categorized physician VAS of response to treatment, and the patient’s perception of being in remission as coded in the GIS. The SMD for the GAS3 step-c showed good discriminatory ability for each external criterion (SMD 1.03-1.22; P < 0.001).

C. Criterion validity Tested
Comparison with a 'gold standard' Continuous scores:
correlations, ROC curves Dichotomus:
Sensitivity & Specificity (Describe)

Criterion validity was assessed using Spearman’s correlation coefficient of the GAS score against the HAQ score and SF-36 physical component summary (SF-36 PCS) and mental component summary (SF-36 MCS). There was strong correlation at 12 months between the GAS3 step-c and the HAQ (r = 0.50; ρ < 0.001) and SF-36 PCS (r = −0.53; ρ < 0.001) and a moderate correlation with the SF-36 MCS (r = −0.30; ρ < 0.001).