VALIDATION DATA

MEASUREMENT PROPERTIES
Limitations
Observations

Ophthalmologists experienced in the care of patients with ocular surface diseases can only perform this examination. Specific staining agents and the slit lamp are necessary

1. RELIABILITY
A. Internal Consistency Not Tested
Cronbach's (Describe)
B. Reliability intraobserver or test-retest Tested
Continuous scores: intraclass
correlation coefficient (ICC)
Dichotomus: Cohen kappa (Describe)

Reliability was assessed in an independent cohort. However, because this score is primarily used as a classification criterion, reliability was assessed 5 years apart to evaluate the stability of the score over time. Intrarater agreement in the precise numerical score was moderate to good (ICC = 0.74; 95% confidence interval [CI] 0.20-0.94).

C. Reliability interobserver or Measurement error Tested
Standard error of measurement (SEM),
smallest detectable change (SDC) or
Limits of agreement (LoA) (Describe)

Interrater numerical agreement was poor (ICC = 0.38; 95% CI −0.25 to 0.78).

2. VALIDITY
A. Content validity: face validity Not Tested
Expert opinion (relevance and
comprehensiveness) (Describe)
B. Construct Validity:
Structural validity
Not Tested
Hypotheses-testing Not Tested
Cross-cultural validity Not Tested
Brief Description
C. Criterion validity Not Tested
Comparison with a 'gold standard' Continuous scores:
correlations, ROC curves Dichotomus:
Sensitivity & Specificity (Describe)