VALIDATION DATA

MEASUREMENT PROPERTIES
Limitations >=5 European languages (English)
Observations
1. RELIABILITY
A. Internal Consistency Tested
Cronbach's (Describe)

Cronbach's alpha for the DAS28 in RA patients was 0.733

B. Reliability intraobserver or test-retest Tested
Continuous scores: intraclass
correlation coefficient (ICC)
Dichotomus: Cohen kappa (Describe)

ICC=0.92

C. Reliability interobserver or Measurement error Tested
Standard error of measurement (SEM),
smallest detectable change (SDC) or
Limits of agreement (LoA) (Describe)

SDD as percentage of mean value of the outcome = 23.2 %

2. VALIDITY
A. Content validity: face validity Tested
Expert opinion (relevance and
comprehensiveness) (Describe)

The DAS28 includes variables from the ACR core set of measures used to assess outcomes in RA. No measures of disability or joint damage are included. 

B. Construct Validity:
Structural validity
Not Tested
Hypotheses-testing Tested
Cross-cultural validity Not Tested
Brief Description
C. Criterion validity Tested
Comparison with a 'gold standard' Continuous scores:
correlations, ROC curves Dichotomus:
Sensitivity & Specificity (Describe)

Regression analysis showed no significant differences between a physician’s and patient’s joint counts and DAS. There were middle to high correlations between patient and physician assessments of tender joints and swollen joints; using R2, this explained 70% of the variance for tender joints and 40% for swollen joints. Kappa analysis showed good agreement between physician and patient assessments of individual joint tenderness (kappa values 0.49–0.84). There was lower agreement for individual swollen joints (kappa values 0.02–0.61).