Detailled Information

Castrejon I, Carmona L, Ortiz AM, Belmonte MA, Martinez-Lopez JA, Gonzalez-Alvaro I. Development and validation of a new disease activity index as a numerical sum of four variables in patients with early arthritis. Arthritis Care Res (Hoboken). 2013;65(4):518–25. Epub 2012/09/25. pmid:23002022.

Cut-Offs and Response Criteria for the Hospital Universitario La Princesa Index (HUPI) and Their Comparison to Widely-Used Indices of Disease Activity in Rheumatoid Arthritis.

This article aims to estimate cut-off points and to establish response criteria for the HUPI in patients with chronic polyarthritis.

The comparative responsiveness of Hospital Universitario Princesa Index and other composite indices for assessing rheumatoid arthritis activity. 

This article aims to evaluate the responsiveness in terms of correlation of the HUPI comparatively to the traditional composite indices used to assess disease activity in RA, and to compare the performance of HUPI-based response criteria with that of the EULAR response criteria.

Biologic therapy response and drug survival for females compared to males with rheumatoid arthritis: a cohort study. 

This article uses the HUPI to eliminate the observed differences in disease activity scores between females and males. 

The Hospital Universitario La Princesa Index (HUPI) is based on the sum of 4 variables graded from 0 to 3: tender joint count, swollen joint count, patient global disease assessment, and erythrocyte sedimentation rate/C‐reactive protein level. The index is feasible and sensitive to change, and could prove superior to previous indices in that it prevents bias arising from sex and missing data.

Sum of 4 variables (graded 0–3): tender joint count, swollen joint count, patient global assessment, and acute‐phase reactants (erythrocyte sedimentation rate [ESR] and/or C‐reactive protein [CRP] level, depending on availability at the moment of evaluation).