| MEASUREMENT PROPERTIES | |
| Limitations | English only |
| Observations | |
| 1. RELIABILITY | |
| A. Internal Consistency | Tested |
| Cronbach's (Describe) |
Cronbach’s α= 0.72-0.94 |
| B. Reliability intraobserver or test-retest | Tested |
| Continuous scores: intraclass correlation coefficient (ICC) Dichotomus: Cohen kappa (Describe) |
ICC= 0.55-0.92 |
| C. Reliability interobserver or Measurement error | Not Tested |
| Standard error of measurement (SEM), smallest detectable change (SDC) or Limits of agreement (LoA) (Describe) |
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| 2. VALIDITY | |
| A. Content validity: face validity | Tested |
| Expert opinion (relevance and comprehensiveness) (Describe) |
Item pool for LupusPRO was derived from patient interviews. The interviews and item pool generation were guided by a medical literature review on SLE and HRQOL/QOL, psychosocial literature in SLE, existing HRQOL/QOL tools, and input from clinicians with backgrounds in lupus/rheumatology and psychology. |
| B. Construct Validity: Structural validity |
Tested |
| Hypotheses-testing | Tested |
| Cross-cultural validity | Not Tested |
| Brief Description |
On principal component analysis (HRQOL items), 6 loadings were observed. Lupus symptoms and cognition items loaded together, whereas physical health and pain-vitality items loaded together. The 6 domains (eigenvalue > 1) explained 72% of the cumulative variance. Similarly, non-HRQOL items loaded on 3 domains and explained 73% of the cumulative variance. Coping and social support domains loaded together. |
| C. Criterion validity | Tested |
| Comparison with a 'gold standard' Continuous scores: correlations, ROC curves Dichotomus: Sensitivity & Specificity (Describe) |
To evaluate criterion validity it was performed correlations of LupusPRO domains and HRQOL score with disease activity and damage measures. Correlation between lupus symptoms domain and disease activity measures ranged from -0.23 to -0.47; correlation of HRQOL score with disease activity measures ranged from -0.29 to -0.32 (see table 2 in the paper for more details) |