VALIDATION DATA

MEASUREMENT PROPERTIES
Limitations <5 European languages (English)
Observations
1. RELIABILITY
A. Internal Consistency Tested
Cronbach's (Describe)

Cronbach’s alpha was 0.81. The two subscales of the 5T-PROs showed satisfying to good internal consistency.

B. Reliability intraobserver or test-retest Tested
Continuous scores: intraclass
correlation coefficient (ICC)
Dichotomus: Cohen kappa (Describe)

The 5T-PRO was administered twice with a time interval of 7 days, and the ICCs ranged from 0.822 (“fatigue” domain) to 0.913 (“general health status” domain) for all the domains in the 5T-PRO.

C. Reliability interobserver or Measurement error Tested
Standard error of measurement (SEM),
smallest detectable change (SDC) or
Limits of agreement (LoA) (Describe)

Agreement between scores was illustrated by Bland and Altman plots, in which the difference between scores was plotted on the y-axis against the average of scores on the x-axis. According to Bland and Altman analysis, there was no systematic error in scores of 5T-PROs

2. VALIDITY
A. Content validity: face validity Tested
Expert opinion (relevance and
comprehensiveness) (Describe)

Overall, the 5T-PROs was correctly completed by most respondents. Less than 3% of each of the 5T-PROs questions had missing values. In subjects who expressed a preference, the majority rated that the tool was easy to fulfill.

B. Construct Validity:
Structural validity
Tested
Hypotheses-testing Tested
Cross-cultural validity Not Tested
Brief Description

The factor analysis revealed a two-factor solution. The first factor, namely, the 5T-PRO physical summary score, accounted for the 35.6 % of the explained variance and represents the patients rating of the grade of pain, disability, and global health perception in different areas of daily life he or she is suffering from. The second factor, the 5T-PROs psychological summary score, accounted for the 26.9 % of the explained variance, representing the patients rating of his medium emotional complaints.

C. Criterion validity Not Tested
Comparison with a 'gold standard' Continuous scores:
correlations, ROC curves Dichotomus:
Sensitivity & Specificity (Describe)