| Name of the Instrument/Tool | Clinical European League Against Rheumatism Sjögren’s Syndrome Disease Activity Index (clinESSDAI) |
| First Description |
Seror R, Meiners P, Baron G, Bootsma H, Bowman SJ, Vitali C, Gottenberg JE, Theander E, Tzioufas A, De Vita S, Ramos-Casals M, Dörner T, Quartuccio L, Ravaud P, Mariette X; EULAR Sjögren Task Force. Development of the ClinESSDAI: a clinical score without biological domain. A tool for biological studies. Ann Rheum Dis, 2016;75(11):1945-1950. |
| Year | 2016 |
| Domains | |
| Concept of constructs | Disease activity |
| Population/Disease | Disease specific |
| Originally developed for | Sjögren's syndrome |
| Other rheumatic diseases where can be applied (only if validated) |
--- |
| Additional population with no rheumatic diseases |
No |
| Language: Originally published in | English |
| Available in Language | English |
| REFERENCE IDENTIFICATION | |
| Author/s | Seror R, Meiners P, Baron G, Bootsma H, Bowman SJ, Vitali C, Gottenberg JE, Theander E, Tzioufas A, De Vita S, Ramos-Casals M, Dörner T, Quartuccio L, Ravaud P, Mariette X; EULAR Sjögren Task Force |
| Title | Development of the ClinESSDAI: a clinical score without biological domain. A tool for biological studies |
| Journal | ARD |
| Year | 2016 |
| Vol | 75 |
| Num | 11 |
| Pages | 1945-1950 |
| Country | UK |
| Language | English |
| Other references of interest | |
| No other References. | |
| Instrument/Tool Translations References | |
| No other References. | |
| DEVELOPER CONTACT INFORMATION | |
| Correspondence to | Raphaèle Seror |
| raphaele.se@gmail.com | |
| Address | Assistance Publique-Hôpitaux de Paris, Université Paris-Sud, (AP-HP), Service de Rhumatologie, Hôpitaux Universitaires Paris-Sud, Center of Research on Immunology of Viral and Autoimmune diseases (IMVA), Le Kremlin Bicêtre, France |
| Website | --- |
| Available | --- |
| Links | --- |
| DESCRIPTION OF THE INSTRUMENT | |
| Type Of Measure | Composite Index |
| Brief Description |
ClinESSDAI is a clinical index based on 11 domains relevant to Sjögren's syndrome (ie, organ systems: cutaneous, respiratory, renal, articular, muscular, peripheral nervous system, central nervous system, haematological, glandular, constitutional, and lymphadenopathy). Each domain is rated in 3 to 4 levels (No, Low, Moderate, High). The PhGA was used as a dependant variable and the explanatory variables included all ESSDAI domains except the biological domain. The weights assigned to each domain were derived from the regression coefficients of the multivariate model and were rounded to form simplified index. |
| Number of Items | 11 |
| Range | 0-135 |
| Responses options/scale |
Yes Each item is rated in 3 to 4 levels (No, Low, Moderate, High) scores being 0-3. |
| Developed for | Both |
| PRACTICAL APPLICATION | |||||||||||||||||||||||||
| Method of administration | Physician | ||||||||||||||||||||||||
| Recommendations to score |
The index is a weighted sum:
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| Score Interpretation | The higher the score, the higher the activity | ||||||||||||||||||||||||
| Cut-off points | Low disease activity (clinESSDAI<5); High disease activity (clinESSDAI≥14) | ||||||||||||||||||||||||
| Cut-off points applied to | --- | ||||||||||||||||||||||||
| Smallest detectable change if described | −3 (95% CI −5 to −2) | ||||||||||||||||||||||||
| Smallest detectable change applied to | --- | ||||||||||||||||||||||||
| Completion time by the patient | - minutes | ||||||||||||||||||||||||
| Scoring time by the assessor | - minutes | ||||||||||||||||||||||||
| Training to score | Not necessary | ||||||||||||||||||||||||
| Strengths | Useful in clinical practice & research | ||||||||||||||||||||||||
| Limitations | --- | ||||||||||||||||||||||||
| OTHER COMMENTS | |
| Other Comments | --- |