VALIDATION DATA

MEASUREMENT PROPERTIES
Limitations >=5 European languages (English)
Observations

EQ-5D-3L Translations >170 languages in self-complete paper format.

EQ-5D-5L Translations >120 languages in self-complete paper format.

EQ-5D-Y Translations > 30 languages.

1. RELIABILITY
A. Internal Consistency Tested
Cronbach's (Describe)

>0.7.

For the EQ-5D-5L, Cronbach’s alpha was 0.86.

B. Reliability intraobserver or test-retest Tested
Continuous scores: intraclass
correlation coefficient (ICC)
Dichotomus: Cohen kappa (Describe)

ICC for the EQ-5D Index:  0.64–0.78

ICC for the EQ-5D VAS: 0.70–0.85

The ICC of the EQ-5D-5 L was 0.828

C. Reliability interobserver or Measurement error Tested
Standard error of measurement (SEM),
smallest detectable change (SDC) or
Limits of agreement (LoA) (Describe)

Bland–Altman plots indicated poor agreement between EQ-5D and SF-6D/15D. In both plots involving EQ-5D, some patients had differences between EQ-5D and the other utility measures exceeding 0.5, a few patients even had a difference of 1.0

2. VALIDITY
A. Content validity: face validity Tested
Expert opinion (relevance and
comprehensiveness) (Describe)

The dimensions were selected after a  detailed examination of existing health status measures, including the Quality of Well-Being Scale, Sickness Impact Profile, Nottingham Health Profile, and Rosser Index. The number of health states in each dimension was deliberately kept to a minimum so that the measure could easily be administered and used for decision making

B. Construct Validity:
Structural validity
Tested
Hypotheses-testing Tested
Cross-cultural validity Tested
Brief Description

Confirmatory Factor Analysis confirmed the robust nature of the EQ-5D and its mono-factorial structure (EFA: Total Variance 50.39% - CFA: chi2 = 3.596; p approximately equal .60; RMSEA = 00; CFI = 1.00; RMR = .007)

C. Criterion validity Not Tested
Comparison with a 'gold standard' Continuous scores:
correlations, ROC curves Dichotomus:
Sensitivity & Specificity (Describe)